Category: Genetics
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SARS-CoV-2 is changing at a glacial pace
SCIENTISTS have had eyes on Sars-CoV-2, the virus that causes Covid-19, since the beginning of this pandemic. They can see it is evolving, but it is happening at a glacial pace compared with two other viruses with pandemic potential: those that cause flu and Aids. That is good news for efforts to develop vaccines and treatments,…
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On the origins of smallpox
THE death date of smallpox is clear. After killing more than 300 million people in the twentieth century, it claimed its last victim in 1978; two years later, on 8 May 1980, the World Health Assembly declared that the variola virus, which causes smallpox, had been eradicated. But the origins of this devastating virus are…
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The flawed brilliance of J.B.S. Haldane
TOWARDS the end of his life, J.B.S. Haldane was inseparable from a pebble that had been found in the Valley of Elah in Israel, where David felled Goliath with a similar projectile. A king-size man who towered over British biology for several decades in the middle of the 20th century, Jack Haldane—the “half-Dane”—was a more…
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Phylloxera – a pest’s genome reveals its past
A CENTURY and a half ago an alien insect alighted in Europe. It displaced millions, ruined local economies and forced scientists, politicians and ordinary folk into a frenzy of defensive activity. Phylloxera, a member of the group known to entomologists as Hemiptera, or “true” bugs (as opposed to all the other critters known colloquially as…
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Europe’s first farmers
EIGHT thousand years ago small bands of seminomadic hunter-gatherers were the only human beings roaming Europe’s lush, green forests. Archaeological digs in caves and elsewhere have turned up evidence of their Mesolithic technology: flint-tipped tools with which they fished, hunted deer and aurochs (a now extinct species of ox), and gathered wild plants. Many had…
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Food, globalisation and pandemics
ONCE a dangerous new pathogen is out, as we are seeing, it can be difficult if not impossible to prevent it going global. One as contagious as SARS-CoV-2 has the potential to infect the whole of humanity. Eighty per cent of cases may be benign, but with such a large pool of susceptible hosts, the…
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Is factory farming to blame for coronavirus?
WHERE did the virus causing the current pandemic come from? How did it get to a food market in Wuhan, China, from where it is thought to have spilled over into humans? The answers to these questions are gradually being pieced together, and the story they tell makes for uncomfortable reading… This article first appeared…
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When will a coronavirus vaccine be ready?
EVEN at their most effective – and draconian – containment strategies have only slowed the spread of the respiratory disease Covid-19. With the World Health Organization finally declaring a pandemic, all eyes have turned to the prospect of a vaccine, because only a vaccine can prevent people from getting sick… This article first appeared in The…
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Your DNA is valuable, why give it away?
THE announcement by 23andMe, a company that sells home DNA testing kits, that it has sold the rights to a promising new anti-inflammatory drug to a Spanish pharmaceutical company is cause for celebration. The collected health data of 23andMe’s millions of customers have potentially produced a medical advance – the first of its kind. But…
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The 2010s: what just happened?
THE 2010s were the decade in which we were reminded that science is just a method, like the rhythm method. And just like the rhythm method, it can be more or less rigorously applied, sabotaged, overrated, underrated and ignored. If you don’t treat it with respect, you may not get the optimal result, but that’s…