Category: Neuroscience

  • On shared memories

    WHAT were the greatest human catastrophes of the 20th century? When asked this question, most people answer the Second World War, followed by the First World War. The former killed around 50 million people, the latter 17 million. But there was another catastrophe that dwarfed both of these, that is rarely mentioned. The influenza pandemic…

  • Roots of brutality

    WHY would an apparently normal young adult drop out of college and turn up some time later in a video performing a cold-blooded execution in the name of jihad? It’s a conundrum we have been forced to ponder ever since a group calling itself ISIS declared war on infidels. But 70 years ago we were…

  • A Faustian bargain

    HUNTINGTON’S disease is awful. It slowly robs its victims of mobility, wits and emotions. And there is no cure. The idea that it might be the obverse of something good sounds, to say the least, counter-intuitive. Yet that is the contention of a small band of neuroscientists who have been studying it. They suggest the…

  • Once upon a time…

    WHAT is “now”? It is an idea that physics treats as a mere illusion, yet it is something we are all familiar with. We tend to think of it as this current instant, a moment with no duration. But if now were timeless, we wouldn’t experience a succession of nows as time passing. Neither would we…

  • Upside down world

    A MAN walks confidently towards an open gate but instead of going straight through he raises his knee very high as if he were stepping over a low wall. He strides forward, reaching out to shake a friend’s hand. But again he misjudges, and his friend draws back in alarm to avoid being punched in…

  • The forgetting gene

    ONE day in 1991, neurologist Warren Strittmatter asked his boss to look at some bewildering data. Strittmatter was studying amyloid-β, the main component of the molecular clumps found in the brains of people with Alzheimer’s disease. He was hunting for amyloid-binding proteins in the fluid that buffers the brain and spinal cord, and had fished…

  • Subtle effects

    MANGANISM has been known about since the 19th century, when miners exposed to ores containing manganese, a silvery metal, began to totter, slur their speech and behave like someone inebriated. The poisoning was irreversible, and soon ended in psychosis and death. Nowadays, the doses workers are exposed to are far lower and manganism is rare.…

  • Don’t cramp my style

    FROM music to medicine is an unusual career path, but Victor Candia is an unusual man. In 1993, when he was preparing to graduate as a guitarist from the University of Music in Trossingen, Germany, he noticed that the fingers of his left hand were starting to curl up as he played. It felt to him…

  • Twilight zone

    ONE day in September 2005 Sarah Tomkins went to the top of the stairs to wave her daughter Caitlin off to the village school. Still in her pyjamas because she was feeling under the weather, she suddenly felt lightheaded. Before six-year-old Caitlin knew what was happening, her mother was lying at the bottom of the…

  • Karma of the crowd

    ON February 10, 2013, overcrowding at a railway station in the northern Indian city of Allahabad led to a stampede that killed 36 people. The city was full at the time. Very full. It was hosting the world’s largest religious gathering, the Maha Kumbh Mela, and the authorities estimated the number of pilgrims in the…