Author: lauraspinney
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The genetic roots of Covid-19
A significant proportion of patients who develop life-threatening forms of Covid-19 have genetic or immunological defects that impair their ability to fight the virus, research has found… This article first appeared in The Guardian on 24 September 2020. To continue reading, click here.
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The strange case of the mutilated horses
THE animals have been found missing ears and genitals, with eyes torn out, or deep, clean cuts to their bodies. The recent spate of horse mutilations reported across France has provoked horror and outrage. Satanic cults have been mooted, or individual perpetrators engaged in copycat crimes. But what if the panic reveals more about our…
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SARS-CoV-2 is changing at a glacial pace
SCIENTISTS have had eyes on Sars-CoV-2, the virus that causes Covid-19, since the beginning of this pandemic. They can see it is evolving, but it is happening at a glacial pace compared with two other viruses with pandemic potential: those that cause flu and Aids. That is good news for efforts to develop vaccines and treatments,…
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The dirty vaccine race
TO begin with, it felt like a sleek performance from a well-honed relay team. On 11 January, only 10 days after reporting a new respiratory disease, the Chinese published the genome sequence of the virus that causes it. Researchers around the world set to work building vaccines against Covid-19, as the disease became known, and…
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The Covid novels are arriving
THE first coronavirus novel from a major British writer has just been published. Summer, the last book in Scottish writer Ali Smith’s seasonal quartet, is infused with the pandemic we are living through. That it has appeared now is a tribute to the agility of both author and publisher, whose goal was to produce literature…
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On the origins of smallpox
THE death date of smallpox is clear. After killing more than 300 million people in the twentieth century, it claimed its last victim in 1978; two years later, on 8 May 1980, the World Health Assembly declared that the variola virus, which causes smallpox, had been eradicated. But the origins of this devastating virus are…
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On plague memory (again)
RUMINATING on why the 1918 flu pandemic wasn’t better remembered, the African historian Terence Ranger concluded in the early 2000s that the story wasn’t being told right. The vast majority of the victims—50 million of them at a conservative count—perished in a mere 13 weeks at the tail end of 1918, all over the globe.…
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The flawed brilliance of J.B.S. Haldane
TOWARDS the end of his life, J.B.S. Haldane was inseparable from a pebble that had been found in the Valley of Elah in Israel, where David felled Goliath with a similar projectile. A king-size man who towered over British biology for several decades in the middle of the 20th century, Jack Haldane—the “half-Dane”—was a more…
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Phylloxera – a pest’s genome reveals its past
A CENTURY and a half ago an alien insect alighted in Europe. It displaced millions, ruined local economies and forced scientists, politicians and ordinary folk into a frenzy of defensive activity. Phylloxera, a member of the group known to entomologists as Hemiptera, or “true” bugs (as opposed to all the other critters known colloquially as…
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‘It’s not over’: intimate diaries from the eye of the UK’s coronavirus storm
WHEN the Oxford team working on a Covid-19 vaccine first started holding weekly catchups in early February, Christina Dold, a 35-year-old senior postdoctoral researcher, jokingly referred to them as “Cobra” meetings. But it was in one of these early sessions that she found out how many volunteers they would be immunising daily, once the vaccine…